WormMine: RNAi WBRNAi00085193

• WormBase ID: WBRNAi00085193
• Phenotype Remark: Depletion of either F38C2.5 or Y57G11C.25 singly by RNAi resulted in no observable phenotype, yet depletion of both genes simultaneously by double RNAi resulted in 100 percent embryonic lethality. RNAi animals appear to produce all tissue types but fail to undergo proper morphogenesis and elongation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00009537	ccch-2	F38C2.5	Caenorhabditis elegans
WBGene00013319	ccch-5	Y57G11C.25	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y57G11C.25	Y57G11C.25	600	IV: 14919624-14919932
CDS:F38C2.5	F38C2.5	561	IV: 16278214-16278534

1 Laboratories

Primary Identifier
TX

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00024645

0 Strain