WormMine: RNAi WBRNAi00112312

• WormBase ID: WBRNAi00112312
• Phenotype Remark: RNAi causes sensitivity to cisplatin.
• Remark: Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006919	vha-10	F46F11.5	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F46F11.5	F46F11.5	381	I: 5609588-5609686

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000010	drug hypersensitive	Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
WBPhenotype:0001796	organism hypersensitive interstrand cross link agents	Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00054080

0 Strain