WormMine: RNAi WBRNAi00097022

• WormBase ID: WBRNAi00097022
• Phenotype Remark: cst-1/2 RNAi resulted in a shortened life span as well as an early-onset, age-associated decline in movement and pharyngeal pumping
• Remark: (Figure 6D-F, Table S2) cst-1/cst-2 RNAi (dsRNA targets both genes)

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00016038	cst-2	C24A8.4	Caenorhabditis elegans
WBGene00017472	cst-1	F14H12.4	Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C24A8.4	C24A8.4	1266	X: 4333192-4333346
CDS:F14H12.4a	F14H12.4a	1488	X: 4339644-4339693
CDS:F14H12.4b	F14H12.4b	1494	X: 4339644-4339693

1 Laboratories

Primary Identifier
LD

3 Phenotype

Identifier	Name	Description
WBPhenotype:0000019	pharyngeal pumping reduced	Pharyngeal pumping motion occurs at a slower rate than control animals.
WBPhenotype:0001171	shortened life span	The duration of viability in the adult phase of the life-cycle is less than that of control animals.
WBPhenotype:0001213	locomotion reduced	Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00027662

1 Strain

WormBase ID
WBStrain00000001