WormMine: RNAi WBRNAi00110667

• WormBase ID: WBRNAi00110667
• Phenotype Remark: Animals were subjected to elo-5 RNAi at later larval stages (L2-L4). The growing worms became progressively sick. The gonads appeared normal at the L4 and early adult stages, but after fertilization of one to ten oocytes, oogenesis became impaired. Gonad degeneration began with a pronounced vacuolization in the midsection of the gonad followed by the appearance of disorganized clumps of nuclei in the proximal part. An egg-laying defect became apparent and only a few progeny arose from these worms, which then arrested at L1.
• Remark: Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001243	elo-5	F41H10.7	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F41H10.7	F41H10.7	825	IV: 5374698-5374788

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000186	oogenesis variant	Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00024532

0 Strain