WormMine: RNAi WBRNAi00077079

• WormBase ID: WBRNAi00077079
• Phenotype Remark: RNAi caused altered organization of actin-containing thin filaments in muscle cells. Adult RNAi-treated worms showed patched or wrinkled sarcomeres, whereas the mocktreated animals exhibited straight and evenly stained filaments, as expected for intact muscle cells.
• Remark: exact sequence used for RNAi not stated by authors, genomic sequence of gene used for curation

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00017244	apy-1	F08C6.6	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F08C6.6	F08C6.6	1068	X: 7568268-7568381

0 Laboratories

3 Phenotype

Identifier	Name	Description
WBPhenotype:0001889	body wall muscle sarcomere morphology variant	Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control.
WBPhenotype:0001570	body wall muscle actin organization defective	The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants.
WBPhenotype:0001354	actin cytoskeleton filament morphology phenotype	Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00031456

0 Strain