WormMine: RNAi WBRNAi00092197

• WormBase ID: WBRNAi00092197
• Genotype: zyg-1(it25); gfp::h2b; gfp::spd-2
• Phenotype Remark: RNAi of skr-1/2 restores about 30% of centrosome duplication to zyg-1(it25) embryos. When centrosome duplication occurred, one centrosome was frequently reduced in size.
• Remark: (Figure 3B, 3D) skr-1/2 RNAi. Authors report that they used an RNAi clone that targeted skr-1 and skr-2 for knockdown, but do not specify which; skr-1 Ahringer clone used for curation

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004807	skr-1	F46A9.5	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F46A9.5	F46A9.5	531	I: 9471564-9471644

1 Laboratories

Primary Identifier
OC

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001903	centrosome biogenesis variant	Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041144

0 Strain