WormMine: RNAi WBRNAi00094446

• WormBase ID: WBRNAi00094446
• Genotype: [sec-23::LacZ-GFP(PTCx)]
• Phenotype Remark: RNAi resulted in increased expression of the PTCx transgene carrying a premature termination codon, indicative of defective mRNA surveillance machinery
• Remark: (Text, data not shown) rpl-41 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004454	rpl-36A	C09H10.2	Caenorhabditis elegans
WBGene00007504	nbs-1	C09H10.10	Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C09H10.10b	C09H10.10b	1080	II: 11095152-11095497
CDS:C09H10.2	C09H10.2	318	II: 11096617-11096677
CDS:C09H10.10a	C09H10.10a	1089	II: 11095152-11095506

1 Laboratories

Primary Identifier
HZ

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001236	transgene expression increased	Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001538	mRNA surveillance defective	Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00040559

0 Strain