WormMine: RNAi WBRNAi00098547

• WormBase ID: WBRNAi00098547
• Phenotype Remark: apb-1 RNAi disrupted acidification of germ cell corpses, as indicated by a lack of staining by the LysoSensor Green DND-189 acidification sensor, suggesting a defect in phagosome maturation
• Remark: (Figure 5A) apb-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000160	apb-1	Y71H2B.10	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y71H2B.10	Y71H2B.10	2868	III: 2584206-2584277

1 Laboratories

Primary Identifier
FU

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001846	phagosome maturation defective	Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.
WBPhenotype:0001394	cell acidification defective	Animals lack the capacity to reduce the internal pH of a cell.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00042428

0 Strain