WormMine: RNAi WBRNAi00113634

• WormBase ID: WBRNAi00113634
• Genotype: hsp-60::GFP
• Phenotype Remark: RNAi knockdown of c30F12.2 activates a mitochondrial unfolded protein response (UPRmt), as indicated by enhanced expression of the UPRmt marker heat shock protein fluorescent reporter hsp-60::GFP, relative to control RNAi (Fig. 7D).
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00016261	C30F12.2	C30F12.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C30F12.2	C30F12.2	1338	I: 6967922-6968062

0 Laboratories

3 Phenotype

Identifier	Name	Description
WBPhenotype:0001236	transgene expression increased	Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001719	unfolded protein response variant	Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
WBPhenotype:0002434	mitochondrial stress response variant	Animals exhibit variations in their response to mitochondrial stress, compared to controls.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00055419

0 Strain