WormMine: RNAi WBRNAi00111496

• WormBase ID: WBRNAi00111496
• Phenotype Remark: After RNAi of ZK721.1 animals showed hypersensitivity to cholesterol limitation. Note ZK721.1/tag-130 is called Cholesterol Uptake Protein-1 (CUP-1) in this paper, but renamed to chup-1. This was shown by alterations in oocyte distribution, a reduction in oocyte numbe, a reduced fertility, increased embryo lethality and a reduction in speed.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006477	chup-1	ZK721.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK721.1	ZK721.1	2271	X: 8792165-8792320

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001766	cholesterol depletion hypersensitive	Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00040950

0 Strain