WormMine: RNAi WBRNAi00106403

• WormBase ID: WBRNAi00106403
• Genotype: unc-45(m94)
• Phenotype Remark: "Treatment of wild-type animals with CeHop and CeAha1 RNAi did not affect myofilament organization (monitored until the second day of adulthood). In contrast, treatment of unc-45(e286) mutant animals with CeHop and CeAha1 RNAi resulted in complete disruption of myofilament organization and MYO-3 mislocalization under permissive conditions (Figure 3C). Similar results were observed for unc-45(m94), although this mutant showed mild myosin disorganization in control animals. CeHop or CeAha1 RNAi-induced myofilament disruption was similar to the MYO3 disorganization observed when unc-45 mutant animals were shifted to restrictive conditions (Figure 3B)."
• Remark: (Figure 3B) sti-1/CeHop RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. If Ahringer clone not available, Vidal laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019983	sti-1	R09E12.3	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R09E12.3	R09E12.3	963	V: 773591-773602

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001889	body wall muscle sarcomere morphology variant	Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control.
WBPhenotype:0001403	antibody subcellular localization variant	Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00046852

0 Strain