WormMine: RNAi WBRNAi00080839

• WormBase ID: WBRNAi00080839
• Genotype: SP12::GFP; histone H2B::CherryRed
• Phenotype Remark: lpin-1(RNAi) led to a disruption of ER structure, with the appearance of membrane sheets, patches and ring or vesicle-like structures. Embryos with a mild nuclear phenotype typically exhibited a stringy ER morphology, with an abundance of ER sheets in place of the tubules network. Embryos with a severe nuclear phenotype exhibited sheet-like ER structures, as well as patches and vesicle-like structure that did not contain DNA.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010425	lpin-1	H37A05.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:H37A05.1	H37A05.1	2385	V: 13650812-13650986

1 Laboratories

Primary Identifier
OCF

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001026	nuclear morphology variation early emb	Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas).
WBPhenotype:0001880	endoplasmic reticulum morphology variant	Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00033438

0 Strain