WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00110660 Phenotype Remark  Knockdown of the EGF receptor (let-23) or its ligand (lin-3) abolishes the lifespan extending effect of royalactin. Royalactin is a glycoprotein essential for the development of long-lived queen honeybees. In C. elegans Royalactin was shown to extend lifespan.
Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002299 let-23 ZK1067.1 Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:ZK1067.1d ZK1067.1d 4008   II: 9197518-9197647
CDS:ZK1067.1b ZK1067.1b 3789   II: 9199189-9199347
CDS:ZK1067.1a ZK1067.1a 3972   II: 9198346-9198460
CDS:ZK1067.1c ZK1067.1c 3987   II: 9197518-9197647

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0001871 drug induced life span variant Life span of the animal is not influenced by drug exposure in the same manner as control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00046137

0 Strain