WormMine: RNAi WBRNAi00110632

• WormBase ID: WBRNAi00110632
• Genotype: NMY-2::GFP
• Phenotype Remark: Authors looked at the dynamics of cortical polarizing flow in the embryo by comparing this flow between wild type and embryos RNAi-depleted for the Rho GTPase activating protein RGA-3. In wild type embryos is flow is predominantly along the long axis of the embryo, while flow in the rga-3 RNAi embryo is orthogonal to this axis.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation. No methods for introduction of RNAi given.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019600	rga-3	K09H11.3	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K09H11.3	K09H11.3	3258	V: 5717905-5718027

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0002004	actomyosin contractility defective	Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals.
WBPhenotype:0001044	cortical dynamics defective early emb	Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00049021

0 Strain