WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00109094 Genotype  mev-1(kn1)
Phenotype Remark  "SIR-2.1 proved to be essentially necessary for the quercetin effects (Fig. 2A). RNAi for any of the four sirtuins in C. elegans displayed no significant influence on lifespan in the absence of glucose and knockdown of sir-2.2, sir-2.3, or sir-2.4 did not block the lifespan rescuing activity of quercetin (data not shown)." Remark  (Figure 2A) sir-2.1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004800 sir-2.1 R11A8.4 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R11A8.4b R11A8.4b 1734   IV: 10363486-10363614
CDS:R11A8.4a R11A8.4a 1824   IV: 10363486-10363614

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0001171 shortened life span The duration of viability in the adult phase of the life-cycle is less than that of control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00044685

0 Strain