WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00114485 Genotype  twk-16p:kin-2(RNAi)
Phenotype Remark  Authors found that stressed-induced sleep (SIS) was reduced when kin-2 was knocked down in twk-16-expressing cell. Remark  Authors used the twk-16 promoter to perform RNAi of kin-2 in specific cells. Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation (R07E4.6a.2).
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002190 kin-2 R07E4.6 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R07E4.6a R07E4.6a 1101   X: 5971695-5971867
CDS:R07E4.6b R07E4.6b 1005   X: 5971695-5971867
CDS:R07E4.6c R07E4.6c 1131   X: 5971695-5971867

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0002433 EGF-induced sleep resistant Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00057039

0 Strain