WormMine: RNAi WBRNAi00110074

• WormBase ID: WBRNAi00110074
• Genotype: Pges-1::gfpmt
• Phenotype Remark: "Therefore, we questioned whether this small increase in the UPRmt might reflect increased mitochondrial biogenesis. To assess this, we used the intestinal mitochondrial reporter Pges-1::gfpmt, which targets GFP into the mitochondria, and performed RNAi against sgk-1. Indeed, sgk-1 RNAi treated worms show increased GFP in the intestine, reflecting increased mitochondrial content at day 1 of adulthood (Figure 7A and B)."
• Remark: (Figure 7) sgk-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004789	sgk-1	W10G6.2	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:W10G6.2a	W10G6.2a	1362	X: 16255015-16255106
CDS:W10G6.2b	W10G6.2b	1392	X: 16255015-16255106

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002267	mitochondrial content increased	Animals exhibit increases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00045812

0 Strain