WormMine: RNAi WBRNAi00109116

• WormBase ID: WBRNAi00109116
• Phenotype Remark: "Estimations of the proteasome activity in the presence of glucose revealed that quercetin caused a significant activation of proteasomal degradation which was completely prevented by the knockdown of sir-2.1 (Fig. 7C)."
• Remark: (Figure 7C) sir-2.1

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004800	sir-2.1	R11A8.4	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R11A8.4b	R11A8.4b	1734	IV: 10363486-10363614
CDS:R11A8.4a	R11A8.4a	1824	IV: 10363486-10363614

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002009	proteasome core activity variant	Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00044685

0 Strain