WormMine: RNAi WBRNAi00108153

• WormBase ID: WBRNAi00108153
• Phenotype Remark: "In sand-1 mutants, no or little endocytosed macromolecules exit from early endosomes, which results in accumulation of endocytic contents in enlarged endosomes (Poteryaev et_al, 2007). Indeed, RNAi against sand-1 induced enlarged RME-8-labeled endosomes with no apparent changes in 2xFYVE-labeled endosomes (Supplemental Figure S3)"

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00018321	sand-1	F41H10.11	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F41H10.11	F41H10.11	1380	IV: 5366868-5367058

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002092	early endosome morphology variant	Any variation in the form or composition of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00036285

0 Strain