WormMine: RNAi WBRNAi00092770

• WormBase ID: WBRNAi00092770
• Genotype: goa-1(n1134); H20-GFP [neuronal marker]
• Phenotype Remark: Morphogenesis does not occur in pop-1(RNAi) embryos. Complex lineage defects in the ABxxa blastomeres were observed. Both ABxxa and ABxxp produced relatively homogenous clones of the predominant tissue type produced by the posterior branches of the wild-type ABxxp lineage. An ABa blastomere isolated by killing all other blastomeres produces large numbers of hypodermal cells and few neurons.
• Remark: (Figure 4, Table 3) pop-1 RNAi. Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004077	pop-1	W10C8.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:W10C8.2	W10C8.2	1317	I: 2823468-2823937

1 Laboratories

Primary Identifier
JJ

7 Phenotype

Identifier	Name	Description
WBPhenotype:0000701	epithelial development variant	Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation.
WBPhenotype:0000816	neuron development variant	Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WBPhenotype:0000414	cell fate transformation	The cell takes on a different identity from which it was initially committed.
WBPhenotype:0000097	AB lineage variant	The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals.
WBPhenotype:0001312	neuron number variant	The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals.
WBPhenotype:0001643	excess hypodermal cells	Embryos generate an excess number of hypodermal cells compared to control.
WBPhenotype:0001136	embryonic morphology variant	Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00002998

0 Strain