WormMine: RNAi WBRNAi00084793

• WormBase ID: WBRNAi00084793
• Genotype: unc-54(r293) smg-1(cc546); rrf-3(pk1426)
• Phenotype Remark: smg-8 RNAi partially suppresses the reduced motility of the unc-54(r293) mutation, indicative of reduced activity of the Nonsense-mediated decay pathway
• Remark: Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010551	smg-8	K04B12.3	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K04B12.3a	K04B12.3a	2622	II: 14441440-14441520
CDS:K04B12.3b	K04B12.3b	2616	II: 14441440-14441520

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000643	locomotion variant	Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
WBPhenotype:0001538	mRNA surveillance defective	Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00037111

0 Strain