WormMine: RNAi WBRNAi00092471

• WormBase ID: WBRNAi00092471
• Phenotype Remark: 44% of air-1 RNAi embryos at the one-cell stage exhibited small spindles. Spindles were designated as "small" if they had smaller centrosomes and/or shorter microtubules (microtubules do not reach the cell cortex) as compared to wild-type spindles at similar stages of the cell cycle
• Remark: (Table 2) air-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000098	air-1	K07C11.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K07C11.2	K07C11.2	981	V: 8221501-8221551

1 Laboratories

Primary Identifier
AG

5 Phenotype

Identifier	Name	Description
WBPhenotype:0001588	microtubule organization biogenesis variant	Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas).
WBPhenotype:0000628	spindle assembly defective early emb	Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
WBPhenotype:0001903	centrosome biogenesis variant	Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.
WBPhenotype:0000759	spindle defective early emb	Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle.
WBPhenotype:0000765	spindle elongation integrity defective early emb	The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00003325

0 Strain