WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085342 Phenotype Remark 
Remark 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003948 pbs-2 C47B2.4 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C47B2.4 C47B2.4 834   I: 12967388-12967642

1 Laboratories

Primary Identifier
OD

20 Phenotype

Identifier Name Description
WBPhenotype:0000688 sterile Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
WBPhenotype:0001260 oocyte morphology variant Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
WBPhenotype:0000313 meiotic progression during oogenesis variant Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis).
WBPhenotype:0001980 germ cell compartment expansion variant Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
WBPhenotype:0001972 germ cell compartment multinucleate Germ cell compartments contain multiple nuclei.
WBPhenotype:0000184 apoptosis fails to occur Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
WBPhenotype:0000182 apoptosis reduced Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0001028 nuclear appearance variant The morphological appearance of nuclei differs from control animals.
WBPhenotype:0001792 nuclei small Nuclei of specific cells are smaller compared to control animals.
WBPhenotype:0001361 chromosome condensation variant Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control.
WBPhenotype:0001945 oocytes small The size of haploid female germ cells (oocytes) are significantly smaller compared to control.
WBPhenotype:0001940 rachis morphology variant Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis.
WBPhenotype:0001973 germ cell compartment size variant Any variation in germ cell compartment size compared to control.
WBPhenotype:0001971 germ cell compartment anucleate Germ cell compartments do not contain a nucleus.
WBPhenotype:0001969 germ cell compartment morphology variant Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes.
WBPhenotype:0001979 gonad vesiculated Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
WBPhenotype:0001956 oocytes lack nucleus Haploid female germ cells (oocytes) lack a nucleus.
WBPhenotype:0001941 rachis narrow The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals.
WBPhenotype:0001942 rachis absent The nucleus-free core of germline cytoplasm in the gonad is missing.
WBPhenotype:0001981 germ cell compartment expansion absent The compartments of the germline do not increase in size.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219