WormMine: RNAi WBRNAi00092828

• WormBase ID: WBRNAi00092828
• Genotype: rde-1(ne215) him-5(e1490) [lag-2::rde-1]
• Phenotype Remark: Authors found that nhr-67 functions cell-autonomously in the linker cell to regulate gonadal migration. In this experiment, authors used rde-1 mutants, which are refractory to RNAi effects, but rescued for rde-1 function cell specifically in the linker cell by a lag-2::rde-1 transgene. These male animals have a gonad migration defect, with none of the linker cells completing the migration by the L4 molt.
• Remark: Because nhr-67 deletion mutants have an embryonic lethal phenotype, authors used RNAi feeding on newly hatched worms to study the function of nhr-67.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003657	nhr-67	C08F8.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C08F8.8	C08F8.8	1251	IV: 11169834-11169870

1 Laboratories

Primary Identifier
PS

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000690	gonad migration variant	Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas).
WBPhenotype:0001511	linker cell migration variant	Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00035457

0 Strain