WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00097638 Phenotype Remark  gck-1(RNAi) animals exhibited a reduction in the number of germ cells overall, with specific reduction in numbers of nuclei in the distal mitotic region, the transition zone, and the pachytene region of the germline. gck-1(RNAi) gonads also contained a large number of nuclei whose stage in meiotic prophase could not be readily determined by morphology or position.
Remark  (Figure 1E, S3 Table S1) gck-1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001526 gck-1 T19A5.2 Caenorhabditis elegans

8 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T19A5.2f T19A5.2f 1959   V: 8947811-8947888
CDS:T19A5.2b T19A5.2b 2412   V: 8948708-8949235
CDS:T19A5.2c T19A5.2c 2409   V: 8948708-8949235
CDS:T19A5.2g T19A5.2g 1914   V: 8949658-8949690
CDS:T19A5.2a T19A5.2a 1962   V: 8947811-8947888
CDS:T19A5.2d T19A5.2d 1917   V: 8949658-8949690
CDS:T19A5.2e T19A5.2e 1902   V: 8951431-8951448
CDS:T19A5.2h T19A5.2h 1899   V: 8951431-8951448

1 Laboratories

Primary Identifier
JS

3 Phenotype

Identifier Name Description
WBPhenotype:0000684 fewer germ cells Germ cell populations are reduced compared to control animals.
WBPhenotype:0001951 pachytene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
WBPhenotype:0001970 germ cell compartment nuclei number variant Germ cell compartments contain an an atypical number on nuclei compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00035301

1 Strain

WormBase ID
WBStrain00000001