WormMine: RNAi WBRNAi00084648

• WormBase ID: WBRNAi00084648
• Phenotype Remark: xpo-1 RNAi results in increased DCR-1 protein levels

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002078	xpo-1	ZK742.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK742.1a	ZK742.1a	3243	V: 7805362-7805882

1 Laboratories

Primary Identifier
HW

10 Phenotype

Identifier	Name	Description
WBPhenotype:0000688	sterile	Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
WBPhenotype:0000031	slow growth	Any variation that causes a reduction in growth rate compared to control.
WBPhenotype:0000062	lethal	Animals die prematurely at any stage of the life cycle.
WBPhenotype:0000136	mRNA levels increased	Animals exhibit elevated levels of messenger RNA compared to control.
WBPhenotype:0000119	protein expression increased	Any change that results in higher than normal levels of protein expression compared to control animals.
WBPhenotype:0000280	breaks in alae	The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas).
WBPhenotype:0001412	alae morphology variant	Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage.
WBPhenotype:0000038	exploded through vulva	The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
WBPhenotype:0001887	excess seam cells	Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals.
WBPhenotype:0000166	seam cell fusion variant	Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation.

2 Phenotype _ Not _ Observed

Identifier	Name	Description
WBPhenotype:0000114	mRNA expression variant	Variations in the biogenesis and stability of messenger RNA molecules compared to control.
WBPhenotype:0001779	miRNA expression variant	Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00036213

0 Strain