WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085349 Phenotype Remark 
Remark 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003401 mpk-1 F43C1.2 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F43C1.2a F43C1.2a 1131   III: 4217396-4217615
CDS:F43C1.2b F43C1.2b 1335   III: 4217396-4217615

1 Laboratories

Primary Identifier
OD

15 Phenotype

Identifier Name Description
WBPhenotype:0000688 sterile Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
WBPhenotype:0000291 no oocytes Hermaphrodites lack fully specialized female gametes that are competent for fertilization.
WBPhenotype:0001951 pachytene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
WBPhenotype:0001972 germ cell compartment multinucleate Germ cell compartments contain multiple nuclei.
WBPhenotype:0000182 apoptosis reduced Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0001952 germline nuclear positioning variant Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control.
WBPhenotype:0001792 nuclei small Nuclei of specific cells are smaller compared to control animals.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0001946 pachytene progression during oogenesis variant Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
WBPhenotype:0001944 oocyte number decreased A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control.
WBPhenotype:0001971 germ cell compartment anucleate Germ cell compartments do not contain a nucleus.
WBPhenotype:0001977 germ cell partition morphology variant Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals.
WBPhenotype:0001978 germ cell partition absent Animals lack germ cell partitions (germ cell compartments).
WBPhenotype:0001954 diplotene absent during oogenesis The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
WBPhenotype:0001943 rachis wide The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219