WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085713 Phenotype Remark 
Remark 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00019608 ani-2 K10B2.5 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:K10B2.5 K10B2.5 3030   II: 6361596-6361680

1 Laboratories

Primary Identifier
OD

20 Phenotype

Identifier Name Description
WBPhenotype:0000688 sterile Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
WBPhenotype:0001260 oocyte morphology variant Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
WBPhenotype:0001668 oocyte accumulation An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control.
WBPhenotype:0001951 pachytene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
WBPhenotype:0000183 apoptosis increased Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0001980 germ cell compartment expansion variant Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
WBPhenotype:0001972 germ cell compartment multinucleate Germ cell compartments contain multiple nuclei.
WBPhenotype:0001180 accumulated germline cell corpses Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WBPhenotype:0001952 germline nuclear positioning variant Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control.
WBPhenotype:0001792 nuclei small Nuclei of specific cells are smaller compared to control animals.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0001945 oocytes small The size of haploid female germ cells (oocytes) are significantly smaller compared to control.
WBPhenotype:0001973 germ cell compartment size variant Any variation in germ cell compartment size compared to control.
WBPhenotype:0001971 germ cell compartment anucleate Germ cell compartments do not contain a nucleus.
WBPhenotype:0001977 germ cell partition morphology variant Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals.
WBPhenotype:0001950 diplotene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
WBPhenotype:0001954 diplotene absent during oogenesis The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
WBPhenotype:0001955 multiple nuclei oocyte Haploid female germ cells (oocytes) contain more than one nucleus.
WBPhenotype:0001956 oocytes lack nucleus Haploid female germ cells (oocytes) lack a nucleus.
WBPhenotype:0001943 rachis wide The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219