WormMine: RNAi WBRNAi00008118

• WormBase ID: WBRNAi00008118
• Phenotype Remark: Observed in >=10% of progeny.
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_7C11

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00012187	rpb-11	W01G7.3	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:W01G7.3	W01G7.3	369	II: 14060090-14060164

1 Laboratories

Primary Identifier
KK

12 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000031	slow growth	Any variation that causes a reduction in growth rate compared to control.
WBPhenotype:0001037	sterile progeny	Any variation that compromises the reproductive ability of the progeny of an animal.
WBPhenotype:0001121	exaggerated asynchrony early emb	Asynchrony of the second division is exaggerated and P1 divides more slowly than normal.
WBPhenotype:0001082	large cytoplasmic granules early emb	Abnormally large granules are observed in the cytoplasm of P0.
WBPhenotype:0001119	cell cycle slow early emb	Embryos take longer to divide during the first and second cell divisions.
WBPhenotype:0000689	maternal sterile	Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
WBPhenotype:0002501	ectopic cleavage furrow early emb	One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001141	nucleus reforms cell division remnant early emb	After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant.
WBPhenotype:0001080	excessive blebbing early emb	Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WBPhenotype:0001083	multiple cytoplasmic cavities early emb	Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis.
WBPhenotype:0001126	cell cell contacts abnormal in four cell embryo	Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001