WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00007572 Phenotype Remark  % penetrance
Remark  PCR product used to make dsRNA was amplified from genomic DNA. Secondary Identifier  PF:GL1_1D10

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004217 ptr-2 C32E8.8 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C32E8.8 C32E8.8 2802   I: 3789414-3789581

1 Laboratories

Primary Identifier
KK

12 Phenotype

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0001177 embryo osmotic pressure sensitive early emb Embryos rupture when placed on a 2% agar pad and covered with a coverslip.
WBPhenotype:0001155 pronuclei meet centrally early emb The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WBPhenotype:0001082 large cytoplasmic granules early emb Abnormally large granules are observed in the cytoplasm of P0.
WBPhenotype:0001143 multiple nuclei early emb Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130 cytokinesis fails early emb Cells of the embryo attempt to divide but fail to form two daughter cells.
WBPhenotype:0000689 maternal sterile Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
WBPhenotype:0001153 pronuclear migration failure early emb Neither of the pronuclei migrate and they never meet.
WBPhenotype:0002501 ectopic cleavage furrow early emb One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001158 pronuclear breakdown asynchronous early emb Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.
WBPhenotype:0001147 polar body defective early emb Polar bodies are abnormal in the inviable one- to four-cell embryo.
WBPhenotype:0001108 P0 spindle rotation failure early emb P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001