WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00076367 Genotype  Punc-54::a-syn::gfp, Punc-54::tor-2
Phenotype Remark  Secondary screen (L3 larvae). RNAi treatment enhanced aggregation of a-syn in worms coexpressing a-syn::GFP and TOR-2. The misfolded protein appeared over developmental time and was randomly distributed in the cytoplasm of the body-wall muscle cells.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00017974 vps-41 F32A6.3 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F32A6.3a F32A6.3a 2280   X: 5286137-5286256
CDS:F32A6.3b F32A6.3b 2046   X: 5286137-5286256
CDS:F32A6.3c F32A6.3c 2706   X: 5283836-5284117

1 Laboratories

Primary Identifier
UA

2 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001405 protein aggregation variant Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00031384

0 Strain