WormMine: RNAi WBRNAi00076446

• WormBase ID: WBRNAi00076446
• Genotype: Punc-54::a-syn::gfp, Punc-54::tor-2
• Phenotype Remark: Secondary screen (L3 larvae). RNAi treatment enhanced aggregation of a-syn in worms coexpressing a-syn::GFP and TOR-2. The misfolded protein appeared over developmental time and was randomly distributed in the cytoplasm of the body-wall muscle cells.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000061	lgc-11	F48E3.7	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F48E3.7	F48E3.7	1305	X: 7503823-7504041

1 Laboratories

Primary Identifier
UA

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001405	protein aggregation variant	Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00031384

0 Strain