WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00076719 Genotype  Punc-54::a-syn::gfp, Punc-54::tor-2
Phenotype Remark  Primary screen (adults). RNAi treatment enhanced aggregation of a-syn in worms coexpressing a-syn::GFP and TOR-2. The misfolded protein appeared over developmental time and was randomly distributed in the cytoplasm of the body-wall muscle cells.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

10 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002015 hsp-16.1 T27E4.8 Caenorhabditis elegans
WBGene00002017 hsp-16.11 T27E4.2 Caenorhabditis elegans
WBGene00006344 sup-39 C15F1.9 Caenorhabditis elegans
WBGene00194993 T27E4.11 T27E4.11 Caenorhabditis elegans
WBGene00044923 T27E4.10 T27E4.10 Caenorhabditis elegans
WBGene00220104 T27E4.22 T27E4.22 Caenorhabditis elegans
WBGene00194994 T27E4.12 T27E4.12 Caenorhabditis elegans
WBGene00014370 F40G12.13 F40G12.13 Caenorhabditis elegans
WBGene00014371 F40G12.14 F40G12.14 Caenorhabditis elegans
WBGene00014317 F08H9.11 F08H9.11 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T27E4.8 T27E4.8 438   V: 9087293-9087604
CDS:T27E4.2 T27E4.2 438   V: 9090115-9090240

1 Laboratories

Primary Identifier
UA

2 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001405 protein aggregation variant Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00031384

0 Strain