WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00090831 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation Remark  (Table S1) F45F2.4/his-7 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

6 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001877 his-3 T10C6.12 Caenorhabditis elegans
WBGene00001881 his-7 F45F2.4 Caenorhabditis elegans
WBGene00001893 his-19 K06C4.11 Caenorhabditis elegans
WBGene00001895 his-21 K06C4.3 Caenorhabditis elegans
WBGene00001925 his-51 F07B7.10 Caenorhabditis elegans
WBGene00001927 his-53 F07B7.3 Caenorhabditis elegans

6 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F45F2.4 F45F2.4 384   V: 8533379-8533762
CDS:F07B7.10 F07B7.10 384   V: 8849788-8850171
CDS:F07B7.3 F07B7.3 384   V: 8853670-8854053
CDS:K06C4.3 K06C4.3 384   V: 8891883-8892266
CDS:K06C4.11 K06C4.11 384   V: 8895765-8896148
CDS:T10C6.12 T10C6.12 384   V: 16040808-16041191

1 Laboratories

Primary Identifier
MZE

3 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain