WormMine: RNAi WBRNAi00090927

• WormBase ID: WBRNAi00090927
• Genotype: unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
• Phenotype Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; GFP::RAB-11 recycling endosomes (REs) distribute evenly or scatter throughout the cell; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated
• Remark: (Table S1) F56D12.1/alh-6 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000112	alh-6	F56D12.1	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F56D12.1d	F56D12.1d	1272	II: 1306385-1306601
CDS:F56D12.1b	F56D12.1b	1539	II: 1307106-1307507
CDS:F56D12.1c	F56D12.1c	1185	II: 1307467-1307514
CDS:F56D12.1a	F56D12.1a	1692	II: 1306385-1306601

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier	Name	Description
WBPhenotype:0001278	transgene expression reduced	Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002095	lysosome-related organelle morphology variant	Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
WBPhenotype:0002107	RAB-11 recycling endosome localization variant	Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041129

0 Strain