WormMine: RNAi WBRNAi00091047

• WormBase ID: WBRNAi00091047
• Genotype: unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
• Phenotype Remark: PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; PEPT-1::DsRED fluorescence intensity reduced; GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescence intensity reduced, possibly less lysosome-related organelles (LROs)
• Remark: (Table S1) F57B9.2/let-711 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002845	let-711	F57B9.2	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F57B9.2b	F57B9.2b	7875	III: 6946816-6946861
CDS:F57B9.2c	F57B9.2c	7005	III: 6949584-6949776
CDS:F57B9.2d	F57B9.2d	5628	III: 6952075-6952404
CDS:F57B9.2a	F57B9.2a	7926	III: 6946765-6946861

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier	Name	Description
WBPhenotype:0001278	transgene expression reduced	Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094	RAB-11 recycling endosome morphology variant	Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002095	lysosome-related organelle morphology variant	Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041129

0 Strain