WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00103853 Genotype  HMR-1::GFP; VAB-10ABD::mCherry
Phenotype Remark  Embryos subjected to ulp-2 RNAi exhibited discontinuous HMR-1::GFP foci and collapsed actin bundles (Figures 7C-7E). In WT embryos, actin bundles are arranged in parallel bands, and HMR-1::GFP is localized at the base of the actin bundle anchoring it to the membrane at AJs. In ulp-2(RNAi) embryos, loss of HMR-1 at the apical junction is accompanied by collapse and random spacing of actin bundles. Remark  (Figure 7C-E) ulp-2 RNAi against exons 1-4 and 15
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006737 ulp-2 Y38A8.3 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y38A8.3b Y38A8.3b 2136   II: 4956006-4956392
CDS:Y38A8.3c Y38A8.3c 1005   II: 4956006-4956392
CDS:Y38A8.3a Y38A8.3a 2682   II: 4956006-4956392

0 Laboratories

2 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002124 circumferential actin bundles disorganized The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00048594

0 Strain