WormMine: RNAi WBRNAi00088795

• WormBase ID: WBRNAi00088795
• Genotype: zyg-1(it25)
• Phenotype Remark: zyg-1(it25);sur-6(RNAi) embryos exhibit both monopolar spindles and asymmetric spindles in which one spindle pole was smaller than the other. The penetrance of the monopolar spindles phenotype increased from 2.9% in zyg-1(it25) embryos to 64% in zyg-1(it25);sur-6(RNAi) embryos. Asymmetric spindles occurred in 8% of embryos.
• Remark: sur-6 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006352	sur-6	F26E4.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F26E4.1	F26E4.1	1488	I: 9754238-9754433

1 Laboratories

Primary Identifier
OC

4 Phenotype

Identifier	Name	Description
WBPhenotype:0000746	cell division variant	Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control.
WBPhenotype:0001903	centrosome biogenesis variant	Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.
WBPhenotype:0001102	mitotic spindle defective early emb	Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle.
WBPhenotype:0001876	centriole biogenesis variant	Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00038325

0 Strain