WormMine: RNAi WBRNAi00092809

• WormBase ID: WBRNAi00092809
• Phenotype Remark: Defects in localization of thick filament and M-line components arise during embryonic elongation and become progressively more severe as development proceeds. This is consistent with preventing proper cytoskeletal reorganization during growth, rather than undermining structural integrity of the M-line.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006814	unc-82	B0496.3	Caenorhabditis elegans

9 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:B0496.3e	B0496.3e	5382	IV: 7424500-7424797
CDS:B0496.3a	B0496.3a	4452	IV: 7428934-7429045
CDS:B0496.3d	B0496.3d	4665	IV: 7428934-7429045
CDS:B0496.3f	B0496.3f	4635	IV: 7428934-7429045
CDS:B0496.3b	B0496.3b	4737	IV: 7428934-7429045
CDS:B0496.3i	B0496.3i	4788	IV: 7431348-7431510
CDS:B0496.3c	B0496.3c	876	IV: 7442423-7442683
CDS:B0496.3g	B0496.3g	4473	IV: 7428934-7429045
CDS:B0496.3h	B0496.3h	4443	IV: 7428934-7429045

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000782	body wall muscle thick filament variant	Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas).
WBPhenotype:0001891	M line variant	Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas).

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00035423

0 Strain