WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091265 Phenotype Remark  Embryonic development arrests during the first cell cycle due to incomplete chromosome segregation. The centrosome cycle appears to be unaffected.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000099 air-2 B0207.4 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:B0207.4 B0207.4 918   I: 5937484-5937551

1 Laboratories

Primary Identifier
CB

4 Phenotype

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000773 chromosome segregation variant Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control.
WBPhenotype:0000040 one cell arrest early emb Embryos fail to divide and arrest as one-cell embryos.
WBPhenotype:0001886 cleavage furrow termination defective early emb Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.

3 Phenotype _ Not _ Observed

Identifier Name Description
WBPhenotype:0001151 pronucleus centrosomes defective early emb Pronucleus is abnormal in the inviable embryo.
WBPhenotype:0001903 centrosome biogenesis variant Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.
WBPhenotype:0001110 aster defective early emb Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores.

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00003548

0 Strain