WormMine: RNAi WBRNAi00114072

• WormBase ID: WBRNAi00114072
• Phenotype Remark: Severe epidermal and neuronal defects
• Remark: (Table S2) arx-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000199	arx-1	Y71F9AL.16	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y71F9AL.16	Y71F9AL.16	1278	I: 2883864-2883959

0 Laboratories

8 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0001908	ventral closure defective	The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo.
WBPhenotype:0001907	dorsal intercalation defective	Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline.
WBPhenotype:0000816	neuron development variant	Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WBPhenotype:0002176	seam cell morphology variant	Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals.
WBPhenotype:0000361	lima bean arrest	Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas).
WBPhenotype:0002569	hypodermis development variant	Any variation in the progression of the hypodermis over time, from its formation to its mature state compared to control.
WBPhenotype:0000367	comma arrest emb	Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas).

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00056424

1 Strain

WormBase ID
WBStrain00047118