WormMine: RNAi WBRNAi00080655

• WormBase ID: WBRNAi00080655
• Genotype: maIs105; nhl-2(ok818); mir-48(n4097); mir-84(n4037)
• Phenotype Remark: RNAi of hbl-1 suppresses the lethality of the let-7 family miRNA mutations. Authors note: Reduction of let-7-family microRNA activity results in a vulval bursting phenotype. If >50% of animals of a given genotype display a vulval bursting phenpotype lethality was scored

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001824	hbl-1	F13D11.2	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F13D11.2a	F13D11.2a	2949	X: 5822277-5822279
CDS:F13D11.2b	F13D11.2b	2883	X: 5823132-5823178

1 Laboratories

Primary Identifier
VT

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000038	exploded through vulva	The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
WBPhenotype:0000060	adult lethal	Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00032974

0 Strain