WormMine: RNAi WBRNAi00008137

• WormBase ID: WBRNAi00008137
• Phenotype Remark: % penetrance range
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_7D7

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019120	npl-4.1	F59E12.4	Caenorhabditis elegans
WBGene00019121	npl-4.2	F59E12.5	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F59E12.5a	F59E12.5a	1584	II: 5622897-5623040
CDS:F59E12.4a	F59E12.4a	1584	II: 5631359-5631502
CDS:F59E12.4b	F59E12.4b	1590	II: 5631359-5631502
CDS:F59E12.5b	F59E12.5b	1590	II: 5622897-5623040

1 Laboratories

Primary Identifier
KK

10 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WBPhenotype:0001121	exaggerated asynchrony early emb	Asynchrony of the second division is exaggerated and P1 divides more slowly than normal.
WBPhenotype:0001082	large cytoplasmic granules early emb	Abnormally large granules are observed in the cytoplasm of P0.
WBPhenotype:0001119	cell cycle slow early emb	Embryos take longer to divide during the first and second cell divisions.
WBPhenotype:0001156	pronuclear size defective early emb	Maternal or paternal pronucleus is either too small or too large.
WBPhenotype:0001080	excessive blebbing early emb	Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WBPhenotype:0001186	embryo delayed at pronuclear contact early emb	Embryos are either delayed or arrested at pronuclear contact.
WBPhenotype:0001150	polar body reabsorbed one two early emb	A polar body is reabsorbed in either the one cell- or the two-cell embryo.
WBPhenotype:0001126	cell cell contacts abnormal in four cell embryo	Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001