WormMine: RNAi WBRNAi00007797

• WormBase ID: WBRNAi00007797
• Phenotype Remark: % penetrance range
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_3G3

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00007710	rsa-1	C25A1.9	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C25A1.9a	C25A1.9a	1215	I: 10185878-10185977
CDS:C25A1.9b	C25A1.9b	1203	I: 10185878-10185977

1 Laboratories

Primary Identifier
KK

17 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0001168	pseudocleavage absent early emb	No pseudocleavage is observed before or during pronuclear migration.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WBPhenotype:0001037	sterile progeny	Any variation that compromises the reproductive ability of the progeny of an animal.
WBPhenotype:0001106	spindle orientation variant AB or P1 early emb	The orientation of the spindle is aberrant in either the AB or the P1 cell.
WBPhenotype:0001155	pronuclei meet centrally early emb	The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WBPhenotype:0001105	P0 spindle position abnormal	Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal.
WBPhenotype:0001143	multiple nuclei early emb	Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130	cytokinesis fails early emb	Cells of the embryo attempt to divide but fail to form two daughter cells.
WBPhenotype:0001123	synchronous second division early emb	AB and P1 divide synchronously.
WBPhenotype:0002501	ectopic cleavage furrow early emb	One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001080	excessive blebbing early emb	Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WBPhenotype:0001158	pronuclear breakdown asynchronous early emb	Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.
WBPhenotype:0001131	loose mitotic furrow early emb	Once formed, the mitotic furrow can "slide"laterally.
WBPhenotype:0001125	P2 EMS synchronous division early emb	P2 and EMS divide synchronously.
WBPhenotype:0001126	cell cell contacts abnormal in four cell embryo	Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.
WBPhenotype:0001113	P1 aster defective early emb	Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001