WormMine: RNAi WBRNAi00022927

• WormBase ID: WBRNAi00022927
• Phenotype Remark: Upon anaphase, two masses of chromatin separated, but extensive chromatin bridges spanned the length of the spindle. Chromosome condensation initiates in prophase in wild-type embryos but is greatly delayed in smc-4(RNAi) embryos.
• Remark: GFP-histone H2B was used to visualize the chromatin
• Secondary Identifier: [cgc5264]:smc-4

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004874	smc-4	F35G12.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F35G12.8	F35G12.8	4650	III: 4587506-4587655

1 Laboratories

Primary Identifier
MG

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0001875	anaphase bridging	Chromosomal masses fail to fully separate and remained linked during anaphase.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005264

1 Strain

WormBase ID
WBStrain00000001