WormMine: RNAi WBRNAi00007532

• WormBase ID: WBRNAi00007532
• Phenotype Remark: % penetrance
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_6A9

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010785	top-2	K12D12.1	Caenorhabditis elegans
WBGene00022854	cin-4	ZK1127.7	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1127.7	ZK1127.7	2529	II: 7038472-7038585
CDS:K12D12.1	K12D12.1	4563	II: 11875157-11875256

1 Laboratories

Primary Identifier
KK

15 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0001106	spindle orientation variant AB or P1 early emb	The orientation of the spindle is aberrant in either the AB or the P1 cell.
WBPhenotype:0001155	pronuclei meet centrally early emb	The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WBPhenotype:0001165	excess maternal pronucleus early emb	One-cell embryos have two or more maternal pronuclei.
WBPhenotype:0001139	nuclear envelope assembly variant early emb	Nuclear envelope does not reassemble properly.
WBPhenotype:0001121	exaggerated asynchrony early emb	Asynchrony of the second division is exaggerated and P1 divides more slowly than normal.
WBPhenotype:0001163	pronucleus formation failure early emb	Either the maternal or paternal pronucleus is absent.
WBPhenotype:0001119	cell cycle slow early emb	Embryos take longer to divide during the first and second cell divisions.
WBPhenotype:0001143	multiple nuclei early emb	Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0002501	ectopic cleavage furrow early emb	One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001156	pronuclear size defective early emb	Maternal or paternal pronucleus is either too small or too large.
WBPhenotype:0001141	nucleus reforms cell division remnant early emb	After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant.
WBPhenotype:0001080	excessive blebbing early emb	Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WBPhenotype:0001161	maternal pronucleus indistinct early emb	Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape.
WBPhenotype:0001126	cell cell contacts abnormal in four cell embryo	Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001