WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00110019 Phenotype Remark  "Next, we performed RNAi against a set of 10 knockdowns previously shown to produce embryonic lethality [icd-1 (inhibitor of celldeath), snr-6 (small nuclear ribonucleoprotein), npp-20 (nuclear pore complex protein), vha-9 (vaculolar ATPase), nap-1 (nucleosome assembly protein), ufd-1 (ubiquitin fusion degradation), fnta-1 (farnesyltransferase), pbs-2 (proteasome b-subunit), cyb-2.1 (cyclin B), and crn-1 (cell death related nuclease)]. In each case, we found embryonic lethality as expected."
Remark  crn-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000794 crn-1 Y47G6A.8 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y47G6A.8 Y47G6A.8 1149   I: 3482030-3482119

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00046120

0 Strain