WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00114548 Phenotype Remark  From Text: "Worms in which riok-1 was knocked down displayed an oogenesis-specific sterility that was associated with several defects in gonad organisation. When riok-1 was knocked down, the number of proliferating mitotic cells was significantly reduced, and the nuclei of germ cells entering the diplotene stage of meiosis prophase I had abnormally organised and large nuclei. In the proximal gonad, oocyte maturation appeared abnormal, and oocytes underwent multiple rounds of DNA replication, resulting in the generation of endomitotic oocytes"
Remark  riok-1 (WBGene00019698) RNAi (ORFeome library RNAi clone)
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00019698 riok-1 M01B12.5 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:M01B12.5a M01B12.5a 1521   I: 3091283-3091814

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000105 oocyte meiotic maturation variant Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00046459

0 Strain