WormMine: RNAi WBRNAi00108058

• WormBase ID: WBRNAi00108058
• Genotype: daf-2(e1370); Psod-3::gfp
• Phenotype Remark: "To test whether PDP-1 modulates transcriptional activity of DAF-16, we used a Psod-3::gfp reporter strain in a daf- 2(e1370) background [51]. daf-2(e1370); Psod-3::gfp worms were grown on vector, pdp-1, daf-18 and daf-16 RNAi and GFP expression was visualized using fluorescence microscopy and scored as low, medium or high (Figure 3B and Figure S8). GFP expression was markedly lower on pdp-1 RNAi compared to vector RNAi, similar to daf-18 and daf-16 RNAi, suggesting that PDP-1 positively modulates DAF-16 transcriptional activity."
• Remark: (Figure 3B, S8B) pdp-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00022832	pdp-1	ZK973.3	Caenorhabditis elegans
WBGene00022834	ZK973.8	ZK973.8	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK973.3	ZK973.3	1356	I: 4368106-4368182

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001278	transgene expression reduced	Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00038374

0 Strain