WormMine: RNAi WBRNAi00094537

• WormBase ID: WBRNAi00094537
• Genotype: alg-1(gk214)
• Phenotype Remark: RNAi of alg-2 in the alg-1(gk214) mutant background results in a depletion of mature let-7 and lin-4 miRNAs as well as an accumulation of lin-4, mir-50, and mir-90 pre-miRNAs
• Remark: (Figure 4B, S4B) alg-2 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000106	alg-2	T07D3.7	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T07D3.7a	T07D3.7a	2733	II: 873212-873266
CDS:T07D3.7b	T07D3.7b	2676	II: 874162-874262

1 Laboratories

Primary Identifier
MJS

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001779	miRNA expression variant	Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.
WBPhenotype:0002155	pre miRNA processing defective	The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041416

0 Strain